Bone Revolution

Helps increase the intestinal absorption of calcium and phosphorous that aids in development and maintenance of bones

Take after low-fibre foods.

Avoid phytates (tubers, legumes, seeds, nuts and unprocessed whole grains such as whole wheat, oats or rice).

Take 3 (three) capsules orally once a day with a glass of water, or consult your healthcare provider.

Take with meals to reduce gastrointestinal effects.

• Calcium salts reduce the absorption of bisphosphonates, sotalol, tetracycline antibiotics, fluoroquinolone antibiotics and quinoline antibiotics; take medication at least 2 hours before or 4-6 hours after calcium supplements.
• Calcium reduces levels of dolutegravir, elvitegravir and levothyroxine; take medication at least 2 hours before or 4-6 hours after calcium supplements.
• Calcium supplementation may decrease the absorption of dietary iron, zinc and magnesium, therefore take calcium supplements at bedtime.
• Calcium enhances the effects of digitalis glycosides on the heart.
• Calcium salts reduce the absorption of fluoride, therefore doses should be separated by at least 3 hours.
• Magnesium can decrease the absorption of bisphosphonates and tetracyclines; separate doses by at least 2 hours.
• Magnesium can form insoluble complexes with quinolones and decrease their absorption; take quinolones at least 2 hours before, or 4-6 hours after magnesium.
• Boron might increase levels of magnesium.
• Zinc at high levels might reduce the absorption of magnesium.
• Zinc can decrease the levels and clinical effects of penicillamine, quinolone antibiotics, tetracycline antibiotics and iron. Take at least 2 hours before, or 4-6 hours after zinc.
• Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs, or other products that have antiplatelet activity.
• Vitamin K can antagonize and reverse the therapeutic effects of warfarin; large doses of vitamin K can reduce the anticoagulant effect of warfarin.
• Vitamin D in high doses can increase magnesium absorption.
• Vitamin D increases the absorption of calcium in the small intestine; excessive amounts of vitamin D might increase the risk of hypercalcaemia. Hypercalcaemia induced by high-doses vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
• There is an increased risk of hypercalcaemia if vitamin D is given with thiazide diuretics, calcium or phosphate.

Take special care if you have:

• Reduced kidney function or kidney disease
• Medical condition associated with high levels of calcium.
• Achlorhydria (no acid in your stomach fluid) - need to take capsules with a meal to increase the absorption of calcium.
• Iodine deficiency - may worsen hypothyroidism
• Chronic liver disease, it may lead to manganese accumulation and toxicity.
• Iron-deficiency anaemia, you might have increased manganese absorption.
• Heart disease.
• Histoplasmosis (an infection due to breathing in spores of a fungus).
• Hyperparathyroidism (high levels of parathyroid hormone in your blood).
• Lymphoma (a type of cancer).
• Sarcoidosis (small patches of red and swollen body tissue).
• Tuberculosis

Is not suitable for use in children.